Video: Never Enough: The Neuroscience and Experience of Addiction | Judy Grisel

Some Takeaways – From Judy:

  • What we know is that addiction is characterized by craving and compulsive use tolerance meaning that the drug works less and less well over time and dependence so that when the drugs go away you feel less good than normal
  • Those things are are mediated by about half of it the risk comes from genetics and the genetic factors include discussed and the tendency toward novelty seeking and risk-taking is higher in adolescents in adults but in some adolescents more than others
  •  How marijuana works on the brain and how homeostasis is maintained so marijuana works THC is the active ingredient that produces the high and it activates this endocannabinoid system that we naturally have so Anandamide and 2-AG are neurotransmitters that interact with places all over the brain all over the cortex and areas associated with learning and memory associated with motivation associated with reward

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